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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jon Hayes* | 531 | 1981-2001 | |
| 2 | Israel Llamas | 456 | 2020-2039 | |
| 3 | John Valley* | 405 | 2021-2042 | |
| 4 | Steve Lawler | 296 | 2029-2044 | |
| 5 | Ismael Estrada* | 274 | 1993-2008 | |
| 6 | Sergio Ramos | 229 | 1986-2003 | |
| 7 | Travis Adams | 227 | 1981-1993 | |
| 8 | Oussama Durieux* | 225 | 1996-2011 | |
| 9 | Bobby Gonzalez | 219 | 2029-2044 | |
| 10 | Maurizio Chiaromonte | 214 | 1987-1997 | |
| 11 | Juan Mendoza | 202 | 1985-2001 | |
| 12 | Kelvin de los Santos | 195 | 2028-2045 | |
| 13 | Matt Beasley | 187 | 2014-2030 | |
| 13 | Edwin Raimundo | 187 | 2022-2031 | |
| 15 | Alfredo Soto | 180 | 1984-1995 | |
| 16 | Juan Castillo* | 178 | 2005-2021 | |
| 17 | Luis Sarabia | 177 | 1993-2006 | |
| 18 | Ignacio Mendoza | 176 | 2003-2018 | |
| 18 | Dave Palacios | 176 | 1990-1997 | |
| 20 | Dustin Brown | 167 | 2027-2044 | |
| 20 | Carlos Rivera | 167 | 2026-2042 | |
| 22 | Adam Frazier | 166 | 2011-2024 | |
| 23 | Yuji Bunion | 161 | 1993-2007 | |
| 23 | Carlton Yingling | 161 | 2032-2044 | |
| 25 | Roberto Esquivel# | 156 | 2035-2050 | |
| 26 | Greg Cane | 152 | 2003-2018 | |
| 27 | Ernesto Lugo | 151 | 1980-1990 | |
| 28 | Arturo Ramirez | 144 | 2006-2021 | |
| 29 | Luis Ramirez | 142 | 2003-2016 | |
| 29 | Danny Urcino | 142 | 2010-2024 | |
| 31 | Joe Lewis | 138 | 1990-2002 | |
| 31 | Tim Shields | 138 | 2002-2013 | |
| 33 | Troy Hahn | 137 | 2026-2039 | |
| 33 | Joe Souders | 137 | 2008-2018 | |
| 35 | Jamie Peters | 130 | 1985-1998 | |
| 36 | Wilson Warner | 128 | 2033-2045 | |
| 37 | Eric Kabacinski | 127 | 1996-2008 | |
| 37 | Kyle Stidham | 127 | 2030-2043 | |
| 39 | Nate Bovill | 126 | 2010-2020 | |
| 40 | Nate Trimble | 124 | 1996-2006 | |
| 41 | Mike Hampton | 123 | 1988-1999 | |
| 42 | Vince Heller | 122 | 2018-2032 | |
| 43 | Tomas Alonso | 121 | 2016-2024 | |
| 44 | Adam Cressman | 118 | 2008-2016 | |
| 45 | Guillermo Sierra | 116 | 2008-2021 | |
| 46 | Josh Pollard | 114 | 1980-1993 | |
| 46 | Chris Robbins | 114 | 2005-2018 | |
| 48 | Steven Connors | 111 | 2013-2023 | |
| 49 | Luis Marte | 110 | 2004-2016 | |
| 50 | Jimmy Lawrence | 109 | 2013-2021 | |
| 51 | Chris Goulet | 108 | 2013-2022 | |
| 52 | Aaron Holeman | 106 | 2029-2041 | |
| 53 | Bill Alonzo | 100 | 1980-1988 | |
| 53 | Chris Kellar | 100 | 1983-1998 | |
| 53 | Gilberto Vega | 100 | 1980-1998 | |
| 56 | Nehemiah Rodinson | 97 | 2005-2021 | |
| 57 | Jorge Guevara | 96 | 2001-2010 | |
| 58 | Luis Irizarry | 94 | 2008-2017 | |
| 58 | Cayden Tano | 94 | 2034-2049 | |
| 60 | Giovonni Rocchigiani* | 93 | 2025-2039 | |
| 60 | Gino Schlepp | 93 | 2029-2039 | |
| 62 | Jim Goudreau | 90 | 2008-2018 | |
| 62 | Alex Roman | 90 | 2013-2022 | |
| 64 | Tyler Ellison | 89 | 2017-2026 | |
| 64 | Steve Haigler | 89 | 1981-1989 | |
| 66 | David Albertson | 88 | 2009-2021 | |
| 67 | Willie Carmona | 87 | 2027-2042 | |
| 68 | Mike Cook | 85 | 1980-1988 | |
| 68 | Juan Huerta | 85 | 1987-1998 | |
| 68 | Tim Manely | 85 | 1982-2000 | |
| 68 | Gilberto Peralta | 85 | 1980-1993 | |
| 72 | Juan Molina | 84 | 1989-2000 | |
| 73 | Gian-Carlo Gabbiadini | 82 | 1991-2000 | |
| 73 | Sergio Mota | 82 | 1999-2004 | |
| 75 | Jonathan Mitchell# | 80 | 2038-2050 | |
| 76 | Rodolfo Camarillo | 79 | 1980-1989 | |
| 76 | Jakob Nero# | 79 | 2038-2050 | |
| 78 | Jeff Knight | 78 | 1994-2003 | |
| 78 | Ismael Villalobos | 78 | 1980-1989 | |
| 80 | Julio Cordero | 77 | 2021-2040 | |
| 80 | Carlos Jo. Wallace | 77 | 1985-1999 | |
| 82 | Ismael Flores | 74 | 1997-2007 | |
| 82 | Antan Penegate | 74 | 1998-2005 | |
| 84 | Stephon Berete | 73 | 1980-1988 | |
| 84 | Bobby Wright | 73 | 1992-2000 | |
| 86 | Al Kaufman | 72 | 1980-1988 | |
| 86 | Bento Pertorini | 72 | 2013-2022 | |
| 88 | Jeff Djuric | 71 | 1980-1989 | |
| 88 | Mike Earwood | 71 | 2004-2015 | |
| 90 | Nicholas Jang# | 70 | 2039-2050 | |
| 90 | Ernesto Villalobos* | 70 | 1985-2000 | |
| 90 | Steve Woods | 70 | 2022-2031 | |
| 93 | Luis Villeda | 69 | 2031-2045 | |
| 94 | Sergio Ramirez | 68 | 1990-2000 | |
| 94 | Greg Webb | 68 | 2022-2028 | |
| 96 | Quadir Gueye | 67 | 1982-1993 | |
| 97 | Cisco Barajas | 66 | 1980-1987 | |
| 97 | Rogelio Ceijas | 66 | 1984-1997 | |
| 97 | Owen Dyche# | 66 | 2042-2050 | |
| 97 | Jacob Wood# | 66 | 2039-2050 |
