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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Juan Molina* | 429 | 1980-1995 | |
| 2 | Jim Lunsford# | 392 | 2041-2050 | |
| 3 | Silky Flores* | 367 | 2007-2021 | |
| 4 | Juan Camacho | 353 | 1987-2002 | |
| 5 | Shane Kinder | 338 | 2007-2019 | |
| 6 | Phil Schmidt | 315 | 1991-2006 | |
| 7 | Juan Guerrero | 313 | 2004-2020 | |
| 7 | Franklin Manrriquez* | 313 | 2010-2032 | |
| 9 | Tim Kaufman | 305 | 1980-1989 | |
| 10 | Danny Estrada | 303 | 1987-2000 | |
| 11 | Jeremy Callen | 299 | 1980-1994 | |
| 12 | Ryan Pruitt | 287 | 2008-2018 | |
| 13 | Eric Campos | 274 | 1981-1995 | |
| 14 | Tony Avery | 273 | 2020-2035 | |
| 15 | Felix Salgado | 265 | 2010-2027 | |
| 16 | Jorge Rocha | 262 | 1983-1996 | |
| 17 | Nate Riley* | 260 | 2004-2021 | |
| 18 | Dave Burns | 258 | 2003-2023 | |
| 19 | Bryan Herman* | 246 | 2016-2032 | |
| 20 | Juan Murillo | 245 | 1988-2008 | |
| 20 | John Schwab | 245 | 2007-2021 | |
| 22 | Sylvester Miles# | 238 | 2041-2050 | |
| 22 | Tomas Urbina# | 238 | 2034-2050 | |
| 24 | Ettore Mercati | 237 | 2016-2029 | |
| 25 | Brad Handy | 233 | 1998-2010 | |
| 26 | Gabe Landry | 224 | 2010-2021 | |
| 27 | Elijah Holt* | 222 | 2022-2042 | |
| 28 | Thurston Reed | 220 | 2030-2045 | |
| 29 | Murdock Bennerman | 216 | 1986-2000 | |
| 30 | Terry Mooney | 211 | 2028-2041 | |
| 31 | Aaron Sanchez | 209 | 2022-2038 | |
| 32 | Ramon Sanchez* | 207 | 2012-2036 | |
| 33 | Joel Medrano | 202 | 1980-1991 | |
| 34 | Ken Gholar | 199 | 2003-2014 | |
| 35 | Damien Escobar# | 196 | 2038-2050 | |
| 36 | David Drury | 194 | 2037-2048 | |
| 36 | Dave Fischer | 194 | 1992-2002 | |
| 38 | Casey Dingley | 191 | 2016-2024 | |
| 38 | Joey Marshall | 191 | 1980-1993 | |
| 40 | Mike Livingston | 190 | 2022-2034 | |
| 41 | Jacob Grimm | 189 | 2038-2050 | |
| 42 | Jerry Smith | 186 | 1981-1992 | |
| 42 | Luis Tamayo | 186 | 1980-1990 | |
| 44 | Luís Montero# | 183 | 2035-2050 | |
| 45 | Brian Chevalier | 180 | 2008-2024 | |
| 46 | Chris Hardman | 178 | 1980-1995 | |
| 47 | Steve Fohner | 177 | 1989-2001 | |
| 48 | Marcos Esmeralda | 176 | 2034-2049 | |
| 49 | Richard Crowe* | 174 | 2032-2048 | |
| 50 | Sergio Cervantes | 171 | 1983-1995 | |
| 50 | Steve Riffel | 171 | 2003-2011 | |
| 52 | Pat Brinkman | 167 | 1992-2003 | |
| 52 | Rafael Pizano | 167 | 2008-2016 | |
| 54 | Manny Moutinho | 166 | 2032-2045 | |
| 55 | Keiran Coleman# | 165 | 2045-2050 | |
| 56 | Maxence Lallement | 164 | 2023-2036 | |
| 56 | Morgan Peirce | 164 | 2039-2049 | |
| 58 | Dan Matheson | 163 | 1999-2012 | |
| 58 | Rogelio Ramirez | 163 | 1981-1994 | |
| 60 | Jody Jackson | 160 | 1999-2011 | |
| 61 | Andy Roberts | 159 | 1993-2006 | |
| 61 | Gary Sheffield | 159 | 2026-2036 | |
| 61 | Edmond Sisson | 159 | 2026-2037 | |
| 64 | Jadon Bodrick | 158 | 2001-2012 | |
| 65 | Robert Gasiewski | 157 | 2014-2021 | |
| 66 | Luis Lamboy | 155 | 1980-1990 | |
| 67 | Mike Meredith | 154 | 1992-2005 | |
| 68 | D.J. Ferrarini | 153 | 2001-2015 | |
| 68 | Juan Garrido | 153 | 2023-2037 | |
| 70 | Jeff Pierucci | 151 | 2015-2022 | |
| 71 | Josué Caballero# | 150 | 2045-2050 | |
| 72 | Belero Aguilar# | 149 | 2046-2050 | |
| 72 | Matt Wooldridge | 149 | 2015-2023 | |
| 74 | Tom Jenkins | 146 | 2026-2036 | |
| 75 | Tom Goldsmith | 145 | 2016-2027 | |
| 75 | Frank Lawrence | 145 | 2021-2031 | |
| 77 | Toby Cloud# | 144 | 2038-2050 | |
| 77 | Keith Moore | 144 | 2015-2026 | |
| 79 | Trevor DiMaggio | 143 | 2023-2035 | |
| 80 | Vinny Medina | 142 | 2018-2031 | |
| 81 | Rogelio Morales | 141 | 1999-2010 | |
| 81 | Josh Walsh | 141 | 1982-1994 | |
| 83 | Darnel Boone | 139 | 2035-2046 | |
| 84 | Edgar Weimer | 135 | 2037-2048 | |
| 85 | Israel Flores | 133 | 2028-2038 | |
| 85 | Latimer Waters# | 133 | 2036-2050 | |
| 87 | Andy Ardon | 132 | 1997-2010 | |
| 87 | Pablo Granda# | 132 | 2040-2049 | |
| 89 | Nate Milton | 129 | 1999-2006 | |
| 89 | Arturo Ramos | 129 | 2003-2009 | |
| 91 | Chad Carney | 128 | 1995-2004 | |
| 91 | Luca Flores# | 128 | 2042-2050 | |
| 91 | Nathan Halker | 128 | 2033-2046 | |
| 91 | Gregory Nelson | 128 | 2035-2042 | |
| 91 | Alejandro Osorio | 128 | 2027-2034 | |
| 96 | Bill Davis | 127 | 2021-2032 | |
| 96 | Jesse McMichael | 127 | 2009-2021 | |
| 98 | Brent Bailey | 126 | 2018-2030 | |
| 98 | Jeff Pope | 126 | 1980-1993 | |
| 98 | Isiah Pugh | 126 | 2035-2045 |
